Investor Overview · Pre-Seed · Confidential

The Hormonal Intelligence Operating System for Women.

Welcome to the age of knowing yourself. Built for the 1.1B women entering menopause globally — with zero centralized support.

See the Product Request Materials

1.1B

Women entering menopause globally by 2030

$60B+

FemTech market projected

Ages 38–65

Core addressable demographic

The Problem

Women Are Blindly Navigating Hormonal Transitions.

Scale of the gap

50M+ women in the U.S. are in perimenopause or menopause — with no centralized digital platform to support them through every stage.

Productivity impact

80% report symptoms — including hot flashes, brain fog, and sleep disruption — impacting work performance. Yet hormone care remains reactive and fragmented.

Diagnostic failure

The average woman sees 3–5 providers before receiving any clarity on the source of her symptoms. Perimenopause can begin in the late 30s — rarely screened that early.

Overlapping crises

Postpartum hormone depletion and early perimenopause frequently overlap for women 38–45 — yet existing apps treat these as entirely separate conditions.

This isn't a wellness gap. It's a multi-billion dollar failure in healthcare and productivity — affecting every woman aged 38 to 65, and it's been ignored for decades.

Founders' Story

We came to Knowher from different life stages — and the same systemic failure.

At 38, one of us was navigating unexplained symptoms that overlapped postpartum recovery and early perimenopause. She was told it was "just stress."

The other was diagnosed with cervical cancer and forced into menopause through treatment — only to discover there was no structured support for what came next.

We realized this wasn't a personal gap. It was a systems gap. Millions of women aged 38–65 are navigating hormonal transitions without clarity, continuity, or predictive care.

We're building the system that should have existed for decades.

Des Wilson-Trueblood and Natalia Salter, co-founders of Knowher

Why Now

The infrastructure exists. The data exists. The demand exists.

The intelligence layer does not. Five forces have converged to make this the exact right moment.

Later Parenthood

Women having children at 38–42 creates unprecedented overlap between postpartum and perimenopause — an entirely unserved cohort.

Wearables at Scale

Wearable adoption is at an all-time high — creating the real-time biometric data layer (including hot flash detection) that Knowher runs on.

AI Personalization

AI-driven personalization is now normalized and expected — the technology for our intelligence engine is ready and proven.

Cultural Shift

Cultural openness around menopause is finally accelerating. The stigma window is closing — the market is opening fast.

Employer Funding

Employers are increasingly funding women's health benefits — unlocking a B2B PMPM channel alongside DTC subscriptions.

The Product OS

Knowher predicts what your body will need before symptoms appear.

Three intelligence pillars working in concert — not a symptom tracker. An operating system for every woman aged 38–65.

Core Platform

Hormonal Intelligence Engine

Symptom + wearable + lab sync
Hot flash tracker — timing, intensity & pattern
Longitudinal tracking & predictive modeling
Horizon Alerts — days before symptoms escalate
Partner alerts (opt-in)

Personalization

Protocol Layer

Nutrition guidance
Movement recommendations
Personalized supplement stack
Sleep health optimization
Behavioral guidance

Monetization Layer

Integrated Ecosystem

Supplement marketplace + affiliate SKUs
Expert AMAs + peer community pods
Coaching hub — hormone, pelvic floor & sex therapy
CVD monitoring (Phase 2)
Telehealth integration (future)

Live Product Demo — Interactive Prototype

Try the Live Demo ↗

Opens in your browser — fully interactive prototype

Meet Sage AI

Your hormonal intelligence companion.

Sage is built into the Knowher OS — a warm, specific, clinically-grounded AI that turns wearable data and symptom logs into personalized, predictive insights. Try a live conversation below.

Not a chatbot. A hormonal intelligence layer.

Sage reads Dana's actual biometric data — sleep, HRV, temperature, hot flash logs — and responds like a knowledgeable friend who has been paying attention for months.

Pattern recognition from real wearable + lab data
Predictive alerts — Sage sees what's coming before Dana does
Protocol adjustments within pre-approved parameters
Evidence-based education in warm, plain language
Community pod suggestions when it feels natural
Professional signposting + appointment prep support

Demo is seeded with sample data for Dana, 47, perimenopause. Sage provides wellness support, not medical advice.

Talk to Sage

Sage provides pattern insights and educational information. Not medical advice.

Market Opportunity

1.1B Women.
Zero Operating System.

Hormonal health for women 38–65 is one of the largest underserved verticals in healthcare — with no longitudinal intelligence layer.

TAM · Total Addressable

$12B

200M digitally engaged midlife women globally · $60/year average annual subscription

SAM · Serviceable

$1.5B

50M+ U.S. women in perimenopause/menopause · 25M digitally active health consumers

SOM · 3 Year Target

$39M+

168,000+ paid subscribers by Y3 · Blended ARPU ~$235/year across 3 tiers

500M

Women currently in peri/menopause globally

50M

U.S. women in peri/menopause

80%

Women control household healthcare decisions

$15T+

Global women's spending power

Business Model

Recurring Subscription Today. Platform Revenue Tomorrow.

Free — Top of Funnel

Free

conversion engine

Feeds the paid funnel

General, unpersonalized content & education
1 free 10-min explainer video
View-only community access
Points earned on engagement — redeemable toward first upgrade

Modeled Revenue Trajectory — Base Scenario

Year 1

45,278

$7.0M Revenue

$2.5M EBITDA · 36% margin

Year 2

98,169

$21.4M Revenue

$9.8M EBITDA · 46% margin

Year 3

168,035

$39.3M Revenue

$19.7M EBITDA · 50% margin

High-margin, recurring, and expanding ARPU.

Blended ARPU ~$19.57/month (25% of subscribers on Premium Plus by Y3). Revenue compounds through subscriptions, coaching commission, branded supplements, marketplace, and B2B — not subscriptions alone.

$39M

ARR Base Case · Y3

The Flywheel

Data Density Builds the Moat.

Every woman who joins makes Knowher smarter for every other woman. The longer they stay, the better it gets — and the harder it is to leave.

User logs symptoms

Wearable + lab sync. Hot flash timing, intensity, duration. Every data point improves the model.

Dataset expands

More engagement = more data. Hormone + lifestyle aggregation. Retention increases as personalization deepens across the 38–65 age span.

Predictive model improves

Recommendations become more accurate. Horizon Alerts fire earlier. Trust compounds over time.

Defensibility grows

Knowher builds the largest longitudinal dataset of women 38–65 navigating hormonal transition. That dataset is the moat.

Product Roadmap

The Knowher Journey.

A phased build — starting with the most critical hormonal moment and expanding into the full intelligence OS.

Phase 1

Month 0–3

Symptom confusion / postpartum / early perimenopause

Phase 2

Month 3–6

App onboarding + conversational logging

Phase 3

Month 6–12

Predictive insight — "what's coming" Horizon Alerts

Phase 4

Month 12–15

Products + coaching — pelvic floor, sex therapy, supplement marketplace

Phase 5

Month 15–18

Personalized protocols — nutritional planning, exercise routines, CVD monitoring

Phase 6

Month 18–21

Long-term retention + data moat — the intelligence engine at full scale

The Ask

Pre-Seed Round.

Raise amount undisclosed. To build the foundational Hormonal Intelligence platform, launch the 3-tier subscription model to 26,000+ waitlisted users, and fund Phase 2 platform expansion — movement, nutrition, CVD monitoring, pelvic floor & sex therapy.

Capital Allocation

Product & Engineering25%

Growth & Community30%

Clinical & Content15%

Operations & Legal8%

Phase 2 Platform Expansion7%

Inventory & Amazon15%

What This Capital Unlocks

Waitlist campaign targeting 26,000+ signups pre-launch

500-woman founding beta cohort (months 1–3)

Full MVP build & public launch on iOS

Phase 2 build — movement, nutrition, CVD monitoring, pelvic floor & sex therapy starting immediately upon funding

45,000+ paying subscribers by Month 12

12-Month Target

$10.6M ARR

45K+ subscribers by M12 — Base scenario

Most pre-seed health platforms raise before they build. We're raising to build it right — with the team, infrastructure, and data model that makes the intelligence layer actually work. Phase 1 UX design & full-stack platform development is fully founder-funded — zero draw on raised capital.

Positioned for institutional Series A at $18M+ ARR within 18 months (Base scenario)

The Team

Built by operators. Driven by experience.

Des Wilson-Trueblood

CEO · Co-Founder

15+ years scaling beauty and CPG brands from zero to exit. As COO of Freck Beauty, grew revenue to $8M, co-led Seed + Series A fundraising, achieved EBITDA-positive, and guided the brand through acquisition. Now a strategic advisor to Freck Beauty.

A Harvard-trained menopause expert and cancer survivor who entered medically induced menopause and navigated the system alone. She didn't build Knowher because it was a market opportunity. She built it because it didn't exist when she needed it most.

Freck Beauty COO Acquired Seed + Series A Sephora Launch Harvard Medical Clio Award 2014

Natalia Salter

CXO · Co-Founder

Founder and creative community operator with 15+ years in the music industry, with deep expertise in storytelling, audience engagement, and cultural insight. In 2024, launched a wellness-focused floristry brand that quickly gained traction and secured a high-profile client base.

Driven by her own experience with perimenopause, Natalia co-founded Knowher to address the lack of modern, personalized support for women navigating hormonal transitions. She is currently leading early product development and investing in the company's growth as it prepares for launch.

Creative Operator Brand Builder Community Architecture Wellness Founder

Get in Touch

Let's build this together.

Knowher is in active conversations. We welcome introductions from aligned investors, strategic partners, and clinical advisors.

Des Wilson-Trueblood · CEO

des@knowherwellness.com

Natalia Salter · CXO

natalia@knowherwellness.com

Request Investor Materials

Full pitch deck, financial model, and one-pager available upon request.

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Investor Access

Non-Disclosure Agreement — Summary